Image - Barts and The London logo and link to home page Image - divider Image - divider
 
  Image - Wolfson Institute of Preventive Medicine title and link to Institute home page
Images - preventive medicine, people
  Image - Centre for Psychiatry title and link to Centre homepage
 
Dave Curtis MD, PhD, MRCPsych
Consultant and Honorary Professor in Psychiatry

Research interests

Psychiatric and statistical genetics, especially as applied to gene-mapping studies of schizophrenia and bipolar disorder. Psychiatric genetic research is carried out in collaboration with Prof Hugh Gurling at University College London.

Also Clinical Director for Adult Mental Health services in Tower Hamlets.

Selected publications

  1. DISC1 association, heterogeneity and interplay in schizophrenia and bipolar disorder. Hennah W, Thomson P, McQuillin A, Bass N, Loukola A, Anjorin A, Blackwood D, Curtis D, Deary IJ, Harris SE, Isometsä ET, Lawrence J, Lönnqvist J, Muir W, Palotie A, Partonen T, Paunio T, Pylkkö E, Robinson M, Soronen P, Suominen K, Suvisaari J, Thirumalai S, Clair DS, Gurling H, Peltonen L, Porteous D. Mol Psychiatry 2008.
  2. Investigation into the ability of SNP chipsets and microsatellites to detect association with a disease locus. Curtis D, Vine AE, Knight J. Ann Hum Genet 2008 72 547-556.
  3. CLUMPHAP: a simple tool for performing haplotype-based association analysis. Knight J, Curtis D, Sham PC. Genet Epidemiol 2008 32 539-545.
  4. Puri V, McQuillin A, Datta S, Choudhury K, Pimm J, Thirumalai S, Krasucki R, Lawrence J, Quested D, Bass N, Crombie C, Fraser G, Walker N, Moorey H, Ray MK, Sule A, Curtis D, Clair DS, Gurling H. Confirmation of the genetic association between the U2AF homology motif (UHM) kinase 1 (UHMK1) gene and schizophrenia on chromosome 1q23.3. Eur J Hum Genet 2008 16 1275-1282.
  5. International Schizophrenia Consortium. Rare chromosomal deletions and duplications increase risk of schizophrenia. Nature 2008 455 237-241.
  6. Ferreira MA, O'Donovan MC, Meng YA, Jones IR, Ruderfer DM, Jones L, Fan J, Kirov G, Perlis RH, Green EK, Smoller JW, Grozeva D, Stone J, Nikolov I, Chambert K, Hamshere ML, Nimgaonkar VL, Moskvina V, Thase ME, Caesar S, Sachs GS, Franklin J, Gordon-Smith K, Ardlie KG, Gabriel SB, Fraser C, Blumenstiel B, Defelice M, Breen G, Gill M, Morris DW, Elkin A, Muir WJ, McGhee KA, Williamson R, Macintyre DJ, Maclean AW, St Clair D, Robinson M, Van Beck M, Pereira AC, Kandaswamy R, McQuillin A, Collier DA, Bass NJ, Young AH, Lawrence J, Nicol Ferrier I, Anjorin A, Farmer A, Curtis D, Scolnick EM, McGuffin P, Daly MJ, Corvin AP, Holmans PA, Blackwood DH; Wellcome Trust Case Control Consortium, Gurling HM, Owen MJ, Purcell SM, Sklar P, Craddock N. Collaborative genome-wide association analysis supports a role for ANK3 and CACNA1C in bipolar disorder. Nat Genet. 2008.
  7. Curtis D, Vine AE, Knight J. A simple method for assessing the strength of evidence for association at the level of the whole gene. Comp Biol Chem 2008 1 115-120.
  8. Datta SR, McQuillin A, Rizig M, Blaveri E, Thirumalai S, Kalsi G, Lawrence J, Bass NJ, Puri V, Choudhury K, Pimm J, Crombie C, Fraser G, Walker N, Curtis D, Zvelebil M, Pereira A, Kandaswamy R, St Clair D, Gurling HM. A threonine to isoleucine missense mutation in the pericentriolar material 1 gene is strongly associated with schizophrenia. Mol Psychiatr. 2008.
 
Top
 
by Wolfson Institute Website Manager © Queen Mary, University of London 2011
Centre for Psychiatry, Old Anatomy Building, Barts and The London, Charterhouse Square, London EC1M 6BQ. Tel: 020 7882 2021 Fax: 020 7882 5728