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Malcolm Law MBBS FRCP FMedSci
Professor of Epidemiology and Preventive Medicine

Professor Malcolm Law qualified in medicine from the University of Adelaide (South Australia), worked in general medicine and chest medicine for some years, trained in epidemiology and preventive medicine with Geoffrey Rose at the London School of Hygiene, and has worked at the Barts site with Professor Wald since 1985.

Much of Professor Law’s work has been in the prevention of coronary heart disease and stroke, with seminal publications on salt and blood pressure, serum cholesterol and heart disease, passive smoking and heart disease, plant sterols and stanols, and the reasons for the low heart disease mortality in France (the French paradox). Quantification of the effects of dietary change and drugs in changing risk factors, of the effects of changing risk factors on the incidence of myocardial infarction and stroke, and of adverse effects of the drugs, has been a prominent feature of his work. Such work, with Professor Wald and other colleagues, led to the calculations of the effect of the Polypill in preventing coronary heart disease events by 88% and stroke by 80%. Bone density and hip fracture, and medical screening, are additional research interests.

Selected publications

  1. Law MR, Frost CD, Wald NJ. By how much does dietary salt reduction lower blood pressure? British Medical Journal 1991;302:811-24.
  2. Law MR, Wald NJ, Thompson SG. The Cholesterol papers British Medical Journal, 1994; 308:363-79.
  3. Law MR, Morris JK, Wald NJ. Environmental tobacco smoke exposure and ischaemic heart disease: an evaluation of the evidence. British Medical Journal 1997; 315:973-80
  4. Law MR, Wald NJ. Why heart disease mortality is low in France: the time lag explanation. British Medical Journal 1999;318:1471-6
  5. Law M. Plant sterol and stanol margarines and health. British Medical Journal 2000; 320: 861-4
  6. Law MR, Wald NJ, Morris JK, Jordan RE. Value of low dose combination treatment with blood pressure lowering drugs: analysis of 354 randomised trials. British Medical Journal 2003;326:1427-31
  7. Law MR, Wald NJ, Rudnicka AR. Quantifying effect of statins on low density lipoprotein cholesterol, ischaemic heart disease and stroke: systematic review and meta-analysis. British Medical Journal 2003;326:1423-7
  8. Law M, Morris JK, Jordan R, Wald N. Headaches and the treatment of blood pressure: results from a meta-analysis of 94 randomized placebo controlled trials with 24 000 participants. Circulation 2005;112:2301-2306
  9. Law M, Rudnicka AR. Statin safety: a systematic review. American Journal of Cardiology 2006;97(suppl):52C-60C
  10. Law M, Withers H, Morris JK, Anderson F. Vitamin D supplementation and the prevention of fractures and falls: results of a randomised trial in elderly people in residential accommodation. Age and Ageing 2006; doi:10.1093/ageing/afj080
 
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Centre for Environmental and Preventive Medicine, Wolfson Institute of Preventive Medicine, Barts and The London, Charterhouse Square, London EC1M 6BQ Tel: 020 7882 3850 Fax: 020 7882 6270